ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

11548

Symbol:

Adra1b

Full Name:

adrenergic receptor, alpha 1b

Alias:

[a]1b

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

11 B1.1|11 19.0 cM

Physical Location:

43588107-43649833 on NC_000077.5, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 147 Symbol (Name): ADRA1B (adrenergic, alpha-1B-, receptor)

Ortholog Status:

The human GeneID 147 is not in current human dataset.

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Alcw3	Acute Alcohol Withdrawal	11	20	16-28 (cM)	4.1	1.00E-05	Significant	PARC
Caws4/Alcw3	Chronic Alcohol Withdrawal	11		15-36 (cM)	6.7	2.00E-07	Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_007416.3	NP_031442.2	NC_000077.5 range: 43588107..43649833, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0000299	integral to membrane of membrane fraction	Cellular Component	IDA (11923452)
GO:0016020	membrane	Cellular Component	IEA
GO:0016021	integral to membrane	Cellular Component	IEA
GO:0004937	alpha1-adrenergic receptor activity	Molecular Function	IMP (9326654\|12782680)
GO:0004937	alpha1-adrenergic receptor activity	Molecular Function	IGI (12782680)
GO:0004937	alpha1-adrenergic receptor activity	Molecular Function	IDA (7911220\|11923452)
GO:0004935	adrenoceptor activity	Molecular Function	IEA
GO:0004930	G-protein coupled receptor activity	Molecular Function	IEA
GO:0004872	receptor activity	Molecular Function	IEA
GO:0004871	signal transducer activity	Molecular Function	IEA
GO:0001584	rhodopsin-like receptor activity	Molecular Function	IEA
GO:0035265	organ growth	Biological Process	IGI (12782680)
GO:0042593	glucose homeostasis	Biological Process	IMP (14581480)
GO:0043278	response to morphine	Biological Process	IMP (11923452)
GO:0045818	negative regulation of glycogen catabolic process	Biological Process	IMP (14581480)
GO:0016049	cell growth	Biological Process	IGI (12782680)
GO:0045819	positive regulation of glycogen catabolic process	Biological Process	IMP (14581480)
GO:0008542	visual learning	Biological Process	IMP (11222061)
GO:0007626	locomotory behavior	Biological Process	IMP (11222061)
GO:0001974	blood vessel remodeling	Biological Process	IMP (15231500)
GO:0001975	response to amphetamine	Biological Process	IMP (11923452\|12871582)
GO:0001987	vasoconstriction of artery involved in baroreceptor response to lowering of systemic arterial blood pressure	Biological Process	IMP (9326654)
GO:0001996	positive regulation of heart rate by epinephrine-norepinephrine	Biological Process	IGI (12782680)
GO:0001997	positive regulation of the force of heart contraction by epinephrine-norepinephrine	Biological Process	IGI (12595294)
GO:0007165	signal transduction	Biological Process	IEA
GO:0007186	G-protein coupled receptor protein signaling pathway	Biological Process	IEA
GO:0007512	adult heart development	Biological Process	IGI (12782680)
GO:0048148	behavioral response to cocaine	Biological Process	IMP (11923452)