ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Adra2a

Full Name:

adrenergic receptor, alpha 2a

Alias:

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

19 D2|19 50.0 cM

Physical Location:

54119722-54123471 on NC_000085.5

Gene Type:

protein-coding

Human Ortholog:

GeneID: 150 Symbol (Name): ADRA2A (adrenergic, alpha-2A-, receptor)

Ortholog Status:

The human GeneID 150 is also in human dataset(s).

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Calw2/Alcdp2	Chronic Alcohol Withdrawal	19	47	36.5-ter (cM)	5.3	6.00E-07	Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_007417.3	NP_031443.3	NC_000085.5 range: 54119722..54123471

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0016021	integral to membrane	Cellular Component	IEA
GO:0016020	membrane	Cellular Component	IEA
GO:0001584	rhodopsin-like receptor activity	Molecular Function	IEA
GO:0005515	protein binding	Molecular Function	IPI (15218143)
GO:0004938	alpha2-adrenergic receptor activity	Molecular Function	TAS (12068299)
GO:0004935	adrenoceptor activity	Molecular Function	IMP (15218143)
GO:0004930	G-protein coupled receptor activity	Molecular Function	IEA
GO:0004872	receptor activity	Molecular Function	IEA
GO:0004871	signal transducer activity	Molecular Function	IEA
GO:0007165	signal transduction	Biological Process	IEA
GO:0007186	G-protein coupled receptor protein signaling pathway	Biological Process	IDA (15218143)
GO:0042596	fear response	Biological Process	IMP (15105370)