ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

11695

Symbol:

Alx4

Full Name:

aristaless 4

Alias:

lst

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

2 E1|2 52.0 cM

Physical Location:

93482590-93518092 on NC_000068.6

Gene Type:

protein-coding

Human Ortholog:

GeneID: 60529 Symbol (Name): ALX4 (aristaless-like homeobox 4)

Ortholog Status:

The human GeneID 60529 is also in human dataset(s).

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Etact1	Alcohol Stimulated Activity	2	51	41-61 (cM)	3.9	2.20E-05	Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_007442.2	NP_031468.1	NC_000068.6 range: 93482590..93518092

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005634	nucleus	Cellular Component	IDA (9374397\|9786416)
GO:0005667	transcription factor complex	Cellular Component	IDA (9847249)
GO:0005667	transcription factor complex	Cellular Component	IPI (11696550)
GO:0003677	DNA binding	Molecular Function	IEA
GO:0046982	protein heterodimerization activity	Molecular Function	IPI (9847249)
GO:0043565	sequence-specific DNA binding	Molecular Function	IDA (9786416)
GO:0005515	protein binding	Molecular Function	IPI (9786416\|11696550)
GO:0003700	transcription factor activity	Molecular Function	IDA (9786416\|9847249\|11696550)
GO:0048705	skeletal morphogenesis	Biological Process	IMP (9374397)
GO:0048704	embryonic skeletal morphogenesis	Biological Process	IGI (9847249\|15728667)
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	Biological Process	IGI (9847249)
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	Biological Process	IDA (9786416\|9847249)
GO:0045449	regulation of transcription	Biological Process	IEA
GO:0048704	embryonic skeletal morphogenesis	Biological Process	IMP (15728667)
GO:0035108	limb morphogenesis	Biological Process	IMP (9374397\|9847249)
GO:0035108	limb morphogenesis	Biological Process	IGI (9847249)
GO:0009952	anterior/posterior pattern formation	Biological Process	IMP (9374397\|9847249)
GO:0009952	anterior/posterior pattern formation	Biological Process	IGI (9847249)
GO:0007517	muscle development	Biological Process	IMP (9374397)
GO:0007275	multicellular organismal development	Biological Process	IEA
GO:0006357	regulation of transcription from RNA polymerase II promoter	Biological Process	IDA (11696550)
GO:0006355	regulation of transcription, DNA-dependent	Biological Process	IEA
GO:0006350	transcription	Biological Process	IEA
GO:0060021	palate development	Biological Process	IGI (9847249)