ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

11920

Symbol:

Atm

Full Name:

ataxia telangiectasia mutated homolog (human)

Alias:

AI256621|C030026E19Rik

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

9 C-D|9 30.0 cM

Physical Location:

53247472-53344677 on NC_000075.5, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 472 Symbol (Name): ATM (ataxia telangiectasia mutated)

Ortholog Status:

The human GeneID 472 is also in human dataset(s).

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Ap5q	Alcohol Preference Drinking	9	25	10-35 (cM)	4.8		Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_007499.2	NP_031525.2	NC_000075.5 range: 53247472..53344677, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005634	nucleus	Cellular Component	TAS (15604234)
GO:0031410	cytoplasmic vesicle	Cellular Component	IEA
GO:0005819	spindle	Cellular Component	IDA (15509711)
GO:0016740	transferase activity	Molecular Function	IEA
GO:0016301	kinase activity	Molecular Function	IEA
GO:0016773	phosphotransferase activity, alcohol group as acceptor	Molecular Function	IEA
GO:0004674	protein serine/threonine kinase activity	Molecular Function	TAS (11040211)
GO:0004672	protein kinase activity	Molecular Function	TAS (15604234)
GO:0004672	protein kinase activity	Molecular Function	IDA (15364958)
GO:0003677	DNA binding	Molecular Function	IEA
GO:0008630	DNA damage response, signal transduction resulting in induction of apoptosis	Biological Process	IMP (11040211\|16777961)
GO:0000077	DNA damage checkpoint	Biological Process	IMP (12937170)
GO:0042159	lipoprotein catabolic process	Biological Process	IGI (15863839)
GO:0043525	positive regulation of neuron apoptosis	Biological Process	IGI (16777961)
GO:0045786	negative regulation of cell cycle	Biological Process	IEA
GO:0008630	DNA damage response, signal transduction resulting in induction of apoptosis	Biological Process	IGI (17476307)
GO:0007507	heart development	Biological Process	IGI (16687486)
GO:0001756	somitogenesis	Biological Process	IGI (16687486)
GO:0006281	DNA repair	Biological Process	IDA (15364958)
GO:0006281	DNA repair	Biological Process	IMP (11679583\|15542845)
GO:0006468	protein amino acid phosphorylation	Biological Process	IDA (15364958)
GO:0006974	response to DNA damage stimulus	Biological Process	TAS (11040211)
GO:0007049	cell cycle	Biological Process	IEA
GO:0007292	female gamete generation	Biological Process	IMP (15640358)
GO:0007420	brain development	Biological Process	IGI (16687486)
GO:0051402	neuron apoptosis	Biological Process	IGI (11248063)