ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

11988

Symbol:

Slc7a2

Full Name:

solute carrier family 7 (cationic amino acid transporter, y+ system), member 2

Alias:

AI158848|Atrc2|Cat2|Tea

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

8 A4|8 21.0 cM

Physical Location:

41947720-42007423 on NC_000074.5

Gene Type:

protein-coding

Human Ortholog:

GeneID: 6542 Symbol (Name): SLC7A2 (solute carrier family 7 (cationic amino acid transporter, y+ system), member 2)

Ortholog Status:

The human GeneID 6542 is not in current human dataset.

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Caws3/Alcw6	Chronic Alcohol Withdrawal	8		16-43 (cM)	3.5	0.0003	Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_001044740.1	NP_001038205.1	NC_000074.5 range: 41947720..42007423
NM_007514.3	NP_031540.2	NC_000074.5 range: 41947720..42007423

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0016021	integral to membrane	Cellular Component	RCA (12466851)
GO:0016021	integral to membrane	Cellular Component	IDA (8187816)
GO:0016021	integral to membrane	Cellular Component	IC (8385111)
GO:0016020	membrane	Cellular Component	IEA
GO:0000064	L-ornithine transmembrane transporter activity	Molecular Function	IDA (8385111)
GO:0015189	L-lysine transmembrane transporter activity	Molecular Function	IDA (8385111)
GO:0015181	arginine transmembrane transporter activity	Molecular Function	IMP (11278602)
GO:0015181	arginine transmembrane transporter activity	Molecular Function	IDA (8195186\|8385111)
GO:0015179	L-amino acid transmembrane transporter activity	Molecular Function	IMP (12675924)
GO:0015179	L-amino acid transmembrane transporter activity	Molecular Function	IDA (15659399)
GO:0015171	amino acid transmembrane transporter activity	Molecular Function	IEA
GO:0005289	high affinity arginine transmembrane transporter activity	Molecular Function	IDA (8195186)
GO:0042116	macrophage activation	Biological Process	IMP (16703566)
GO:0002537	production of nitric oxide during acute inflammatory response	Biological Process	IMP (11278602\|17003120)
GO:0006809	nitric oxide biosynthetic process	Biological Process	IMP (12675924)
GO:0006810	transport	Biological Process	IEA
GO:0015822	ornithine transport	Biological Process	IDA (8385111)
GO:0015819	lysine transport	Biological Process	IDA (8385111)
GO:0015809	arginine transport	Biological Process	IMP (11278602\|12675924)
GO:0015809	arginine transport	Biological Process	IDA (8195186\|8385111)
GO:0015807	L-amino acid transport	Biological Process	IDA (15659399)
GO:0006865	amino acid transport	Biological Process	IEA
GO:0050727	regulation of inflammatory response	Biological Process	IMP (17003120)