ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Cacna1e

Full Name:

calcium channel, voltage-dependent, R type, alpha 1E subunit

Alias:

A430040I15|BII|Cach6|Cacnl1a6|Cav2.3|Cchra1|alpha1E

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

1 G3|1 86.0 cM

Physical Location:

156239648-156573049 on NC_000067.5, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 777 Symbol (Name): CACNA1E (calcium channel, voltage-dependent, R type, alpha 1E subunit)

Ortholog Status:

The human GeneID 777 is not in current human dataset.

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Ap1q	Alcohol Preference Drinking	1	76	45-95 (cM)	4.5		Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_009782.3	NP_033912.2	NC_000067.5 range: 156239648..156573049, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0016021	integral to membrane	Cellular Component	RCA (12466851)
GO:0016020	membrane	Cellular Component	IEA
GO:0005891	voltage-gated calcium channel complex	Cellular Component	TAS (11296258)
GO:0005216	ion channel activity	Molecular Function	IEA
GO:0047485	protein N-terminus binding	Molecular Function	IPI (15258581)
GO:0005509	calcium ion binding	Molecular Function	IEA
GO:0005262	calcium channel activity	Molecular Function	IEA
GO:0005245	voltage-gated calcium channel activity	Molecular Function	IMP (12827191)
GO:0005244	voltage-gated ion channel activity	Molecular Function	IEA
GO:0006811	ion transport	Biological Process	IEA
GO:0006816	calcium ion transport	Biological Process	IMP (12827191)
GO:0042593	glucose homeostasis	Biological Process	IMP (11735114)
GO:0006810	transport	Biological Process	IEA