| Gene Information |
| Gene ID: | | 12355 |
| Symbol: | | Nr1i3 |
| Full Name: | | nuclear receptor subfamily 1, group I, member 3 |
| Alias: | | AA209988|AI551208|CAR|CAR-beta|Care2|ESTM32|MB67|MGC107281 |
| Organism: | | Mus musculus (Mouse) |
| Chromosome: | | 1 |
| Genetic Location: | | 1 H3|1 92.6 cM |
| Physical Location: | | 173144100-173148974 on NC_000067.5 |
| Gene Type: | | protein-coding |
| Human Ortholog: | | GeneID: 9970 Symbol (Name): NR1I3 (nuclear receptor subfamily 1, group I, member 3) |
| Ortholog Status: | | The human GeneID 9970 is not in current human dataset. |
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| Gene in Ethanol Study Datasets |
| QTL Information | | QTL | Phenotype | Chr | Peak (cM) | LOD | P Value | Range | Status | QTL Link | |
| Alcw1 | Acute Alcohol Withdrawal | 1 | 96 | 172.3-176.5 (Mb) | 5.6 | 3.00E-07 | Significant | PARC | | Calw1/Alcdp1 | Chronic Alcohol Withdrawal | 1 | 96 | 89-106.3 (cM) | 7.6 | 2.00E-09 | Significant | PARC | | Ap1q | Alcohol Preference Drinking | 1 | 76 | 45-95 (cM) | 4.5 | | Significant | PARC |
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| Gene Refseq Sequence Annotation |
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| Gene Ontology (GO) Annotation |
| GO ID | GO Term | Category | Evidence (PubMed) | |
| GO:0005829 | cytosol | Cellular Component | IDA (12885400) | |
| GO:0005634 | nucleus | Cellular Component | IDA (12885400) | |
| GO:0043565 | sequence-specific DNA binding | Molecular Function | IEA | |
| GO:0008270 | zinc ion binding | Molecular Function | IEA | |
| GO:0003677 | DNA binding | Molecular Function | IDA (11891224) | |
| GO:0005515 | protein binding | Molecular Function | IPI (11891224|12885400) | |
| GO:0004879 | ligand-dependent nuclear receptor activity | Molecular Function | IEA | |
| GO:0004872 | receptor activity | Molecular Function | IEA | |
| GO:0003707 | steroid hormone receptor activity | Molecular Function | IEA | |
| GO:0003700 | transcription factor activity | Molecular Function | IEA | |
| GO:0046872 | metal ion binding | Molecular Function | IEA | |
| GO:0006350 | transcription | Biological Process | IEA | |
| GO:0006355 | regulation of transcription, DNA-dependent | Biological Process | IEA | |
| GO:0016481 | negative regulation of transcription | Biological Process | IDA (11891224) | |
| GO:0045449 | regulation of transcription | Biological Process | IDA (11891224) | |
|
| Other Database Cross Links |
| NCBI Entrez Gene: | | 12355 |
| MGI: | |
| Ensembl: | | ENSMUSG00000005677 |
| dbSNP: | | Nr1i3 |
| AceView: | | Nr1i3 |
