ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Casp7

Full Name:

caspase 7

Alias:

AI314680|CMH-1|ICE-IAP3|Mch3|caspase-7|mCASP-7

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

19 D2|19 50.0 cM

Physical Location:

56471618-56516833 on NC_000085.5

Gene Type:

protein-coding

Human Ortholog:

GeneID: 840 Symbol (Name): CASP7 (caspase 7, apoptosis-related cysteine peptidase)

Ortholog Status:

The human GeneID 840 is not in current human dataset.

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Calw2/Alcdp2	Chronic Alcohol Withdrawal	19	47	36.5-ter (cM)	5.3	6.00E-07	Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_007611.2	NP_031637.1	NC_000085.5 range: 56471618..56516833

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005737	cytoplasm	Cellular Component	IEA
GO:0008233	peptidase activity	Molecular Function	IEA
GO:0030693	caspase activity	Molecular Function	RCA (12819136)
GO:0030693	caspase activity	Molecular Function	IDA (16183742)
GO:0016787	hydrolase activity	Molecular Function	IEA
GO:0008234	cysteine-type peptidase activity	Molecular Function	IEA
GO:0009411	response to UV	Biological Process	IGI (16469926)
GO:0001836	release of cytochrome c from mitochondria	Biological Process	IGI (16469926)
GO:0007507	heart development	Biological Process	IGI (16469926)
GO:0006917	induction of apoptosis	Biological Process	RCA (12819136)
GO:0006917	induction of apoptosis	Biological Process	IGI (16469926)
GO:0006915	apoptosis	Biological Process	IEA
GO:0006508	proteolysis	Biological Process	RCA (12819136)
GO:0042981	regulation of apoptosis	Biological Process	RCA (12819136)