ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Runx3

Full Name:

runt related transcription factor 3

Alias:

AML2|Cbfa3|Pebp2a3

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

4 D3|4 65.7 cM

Physical Location:

134676559-134733904 on NC_000070.5

Gene Type:

protein-coding

Human Ortholog:

GeneID: 864 Symbol (Name): RUNX3 (runt-related transcription factor 3)

Ortholog Status:

The human GeneID 864 is not in current human dataset.

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Ap3q	Alcohol Preference Drinking	4	75	65-ter (cM)	4.6		Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_019732.2	NP_062706.2	NC_000070.5 range: 134676559..134733904

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005634	nucleus	Cellular Component	IDA (15514019)
GO:0003677	DNA binding	Molecular Function	IDA (12807883)
GO:0003700	transcription factor activity	Molecular Function	IEA
GO:0005524	ATP binding	Molecular Function	IEA
GO:0048469	cell maturation	Biological Process	IGI (15107406)
GO:0045786	negative regulation of cell cycle	Biological Process	IMP (11955451)
GO:0031175	neurite development	Biological Process	IMP (12352981)
GO:0031069	hair follicle morphogenesis	Biological Process	IMP (15937937)
GO:0007411	axon guidance	Biological Process	IMP (12352981)
GO:0006917	induction of apoptosis	Biological Process	IMP (11955451)
GO:0006355	regulation of transcription, DNA-dependent	Biological Process	IEA
GO:0006350	transcription	Biological Process	IEA
GO:0050680	negative regulation of epithelial cell proliferation	Biological Process	IMP (11955451)