ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Cdkn2b

Full Name:

cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)

Alias:

AV083695|INK4b|MTS2|p15|p15(INK4b)|p15INK4b

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

4 C3-C6|4 42.7 cM

Physical Location:

88952228-88956862 on NC_000070.5, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 1030 Symbol (Name): CDKN2B (cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4))

Ortholog Status:

The human GeneID 1030 is not in current human dataset.

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Caws2	Chronic Alcohol Withdrawal	4		33-51 (cM)	2.3	0.005	Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_007670.3	NP_031696.1	NC_000070.5 range: 88952228..88956862, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0003677	DNA binding	Molecular Function	RCA (12466851)
GO:0003700	transcription factor activity	Molecular Function	RCA (12466851)
GO:0016301	kinase activity	Molecular Function	IEA
GO:0006355	regulation of transcription, DNA-dependent	Biological Process	RCA (12466851)
GO:0007049	cell cycle	Biological Process	IEA
GO:0045786	negative regulation of cell cycle	Biological Process	IEA