ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Cebpd

Full Name:

CCAAT/enhancer binding protein (C/EBP), delta

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

16 A2|16 9.0 cM

Physical Location:

15887378-15889637 on NC_000082.5

Gene Type:

protein-coding

Human Ortholog:

GeneID: 1052 Symbol (Name): CEBPD (CCAAT/enhancer binding protein (C/EBP), delta)

Ortholog Status:

The human GeneID 1052 is not in current human dataset.

Gene in Ethanol Study Datasets

Gene Information

Original ID1:		X61800
Fold Change:		1.9, 1.6, 3.0, 2.3
Note:		4 fold changes are from C57BL/6J trial 1, C57BL/6J trial 2, DBA/2J trial 1, DBA/2J trial 2

Dataset Information

Name:		15002731
Method:		Microarray
Tissue:		Whole brain
Phenotype:		Acute ethanol response
Publication:		Treadwell et al. Neurochem Res. (2004) Microarray analysis of mouse brain gene expression following acute ethanol treatment. PubMed
Summary:		We have analyzed the expression of approximately 24,000 genes using oligonucleotide microarrays to examine the brain expression profiles in two strains of inbred mice, C57BL/6J and DBA/2J, following exposure to an acute dose of ethanol. Our screen identified 61 genes responding to the ethanol treatment beyond a 1.5-fold threshold, with 46 genes altered in both mouse strains and 15 altered in only one strain.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_007679.4	NP_031705.3	NC_000082.5 range: 15887378..15889637

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005634	nucleus	Cellular Component	IDA (11940593\|12821655)
GO:0003677	DNA binding	Molecular Function	IDA (12821655)
GO:0003700	transcription factor activity	Molecular Function	IEA
GO:0042803	protein homodimerization activity	Molecular Function	IDA (12821655)
GO:0043565	sequence-specific DNA binding	Molecular Function	IEA
GO:0046982	protein heterodimerization activity	Molecular Function	IDA (12177065)
GO:0046983	protein dimerization activity	Molecular Function	IEA
GO:0006350	transcription	Biological Process	IEA
GO:0006355	regulation of transcription, DNA-dependent	Biological Process	IEA