ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Cflar

Full Name:

CASP8 and FADD-like apoptosis regulator

Alias:

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

1 C1.3|1 30.1 cM

Physical Location:

58770129-58815727 on NC_000067.5

Gene Type:

protein-coding

Human Ortholog:

GeneID: 8837 Symbol (Name): CFLAR (CASP8 and FADD-like apoptosis regulator)

Ortholog Status:

The human GeneID 8837 is also in human dataset(s).

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Caws1/Alcw5	Chronic Alcohol Withdrawal	1		28-47 (cM)	6.5	3.00E-07	Significant	PARC

Gene Refseq Sequence Annotation

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005737	cytoplasm	Cellular Component	IDA (16263940)
GO:0005515	protein binding	Molecular Function	IPI (16469705)
GO:0008234	cysteine-type peptidase activity	Molecular Function	IEA
GO:0030693	caspase activity	Molecular Function	IEA
GO:0006508	proteolysis	Biological Process	IEA
GO:0006915	apoptosis	Biological Process	RCA (12819136)
GO:0042981	regulation of apoptosis	Biological Process	RCA (12819136)
GO:0043066	negative regulation of apoptosis	Biological Process	IMP (16263940)
GO:0043154	negative regulation of caspase activity	Biological Process	IMP (16263940)