ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Chrm4

Full Name:

cholinergic receptor, muscarinic 4

Alias:

Chrm-4|M4

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

2 E1|2 49.0 cM

Physical Location:

91767405-91768844 on NC_000068.6

Gene Type:

protein-coding

Human Ortholog:

GeneID: 1132 Symbol (Name): CHRM4 (cholinergic receptor, muscarinic 4)

Ortholog Status:

The human GeneID 1132 is also in human dataset(s).

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Etact1	Alcohol Stimulated Activity	2	51	41-61 (cM)	3.9	2.20E-05	Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_007699.2	NP_031725.1	NC_000068.6 range: 91767405..91768844

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0045211	postsynaptic membrane	Cellular Component	IEA
GO:0045202	synapse	Cellular Component	IEA
GO:0030054	cell junction	Cellular Component	IEA
GO:0016021	integral to membrane	Cellular Component	RCA (12466851)
GO:0016020	membrane	Cellular Component	IEA
GO:0001584	rhodopsin-like receptor activity	Molecular Function	IEA
GO:0004981	muscarinic acetylcholine receptor activity	Molecular Function	IEA
GO:0004930	G-protein coupled receptor activity	Molecular Function	IEA
GO:0004872	receptor activity	Molecular Function	IEA
GO:0004871	signal transducer activity	Molecular Function	IEA
GO:0007165	signal transduction	Biological Process	IEA
GO:0007186	G-protein coupled receptor protein signaling pathway	Biological Process	IEA