ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Chuk

Full Name:

conserved helix-loop-helix ubiquitous kinase

Alias:

AI256658|Chuk1|Fbx24|Fbxo24|IKK-1|IKK-alpha|IKK1|IKK[a]|IKKalpha

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

19 C3|19 45.0 cM

Physical Location:

44147825-44181934 on NC_000085.5, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 1147 Symbol (Name): CHUK (conserved helix-loop-helix ubiquitous kinase)

Ortholog Status:

The human GeneID 1147 is not in current human dataset.

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Calw2/Alcdp2	Chronic Alcohol Withdrawal	19	47	36.5-ter (cM)	5.3	6.00E-07	Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_007700.1	NP_031726.1	NC_000085.5 range: 44147825..44181934, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005737	cytoplasm	Cellular Component	TAS (9597130)
GO:0005634	nucleus	Cellular Component	IEA
GO:0016740	transferase activity	Molecular Function	IEA
GO:0016301	kinase activity	Molecular Function	IEA
GO:0008384	IkappaB kinase activity	Molecular Function	IEA
GO:0000166	nucleotide binding	Molecular Function	IEA
GO:0005524	ATP binding	Molecular Function	IEA
GO:0005515	protein binding	Molecular Function	IPI (10733566\|15102471\|16612387)
GO:0004672	protein kinase activity	Molecular Function	IDA (15684432)
GO:0004674	protein serine/threonine kinase activity	Molecular Function	IEA
GO:0004702	receptor signaling protein serine/threonine kinase activity	Molecular Function	TAS (9597130)
GO:0007252	I-kappaB phosphorylation	Biological Process	TAS (9597130)
GO:0006468	protein amino acid phosphorylation	Biological Process	IEA
GO:0002011	morphogenesis of an epithelial sheet	Biological Process	IMP (14960276)
GO:0030316	osteoclast differentiation	Biological Process	IGI (15485831)
GO:0030316	osteoclast differentiation	Biological Process	IMP (15485831)
GO:0042475	odontogenesis of dentine-containing teeth	Biological Process	IMP (14960276)