ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Ccr4

Full Name:

chemokine (C-C motif) receptor 4

Alias:

CHEMR1|Cmkbr4|LESTR|MGC151418|Sdf1r

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

9 F3|9 61.0 cM

Physical Location:

114400739-114405663 on NC_000075.5, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 1233 Symbol (Name): CCR4 (chemokine (C-C motif) receptor 4)

Ortholog Status:

The human GeneID 1233 is also in human dataset(s).

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Etact2	Alcohol Stimulated Activity	9	61	51-71 (cM)	3.6	4.30E-05	Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_009916.2	NP_034046.2	NC_000075.5 range: 114400739..114405663, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0016021	integral to membrane	Cellular Component	RCA (12466851)
GO:0016020	membrane	Cellular Component	IEA
GO:0001584	rhodopsin-like receptor activity	Molecular Function	IEA
GO:0016493	C-C chemokine receptor activity	Molecular Function	IMP (10811868)
GO:0004945	angiotensin type II receptor activity	Molecular Function	IEA
GO:0004930	G-protein coupled receptor activity	Molecular Function	IEA
GO:0004872	receptor activity	Molecular Function	IEA
GO:0004871	signal transducer activity	Molecular Function	IEA
GO:0006954	inflammatory response	Biological Process	IMP (10811868)
GO:0007165	signal transduction	Biological Process	IEA
GO:0007186	G-protein coupled receptor protein signaling pathway	Biological Process	IEA
GO:0002507	tolerance induction	Biological Process	IMP (15809349)
GO:0001764	neuron migration	Biological Process	IMP (16262623)
GO:0006935	chemotaxis	Biological Process	IMP (10811868)