ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Col2a1

Full Name:

collagen, type II, alpha 1

Alias:

Col2a|Col2a-1|Del1|Dmm|MGC90638

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

15 F1|15 54.5 cM

Physical Location:

97805401-97835075 on NC_000081.5, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 1280 Symbol (Name): COL2A1 (collagen, type II, alpha 1)

Ortholog Status:

The human GeneID 1280 is not in current human dataset.

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Lore5	Alcohol-induced Loss of Righting Reflex	15		18.8-61.7 (cM)	4		Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_031163.3	NP_112440.2	NC_000081.5 range: 97805401..97835075, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005615	extracellular space	Cellular Component	RCA (12466851)
GO:0005737	cytoplasm	Cellular Component	IDA (12799063\|14614991)
GO:0031012	extracellular matrix	Cellular Component	IDA (16079159)
GO:0005615	extracellular space	Cellular Component	IDA (12799063\|14614991)
GO:0005581	collagen	Cellular Component	IEA
GO:0005578	proteinaceous extracellular matrix	Cellular Component	IEA
GO:0005576	extracellular region	Cellular Component	IEA
GO:0005201	extracellular matrix structural constituent	Molecular Function	IEA
GO:0005198	structural molecule activity	Molecular Function	IEA
GO:0030199	collagen fibril organization	Biological Process	IMP (3070812)
GO:0010468	regulation of gene expression	Biological Process	IMP (9299161)
GO:0006817	phosphate transport	Biological Process	IEA
GO:0006029	proteoglycan metabolic process	Biological Process	IMP (3070812)
GO:0001502	cartilage condensation	Biological Process	IMP (3070812)
GO:0043066	negative regulation of apoptosis	Biological Process	IMP (9299161)