ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

12912

Symbol:

Creb1

Full Name:

cAMP responsive element binding protein 1

Alias:

2310001E10Rik|3526402H21Rik|AV083133|Creb|Creb-1

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

1 C2|1 31.0 cM

Physical Location:

64579377-64651121 on NC_000067.5

Gene Type:

protein-coding

Human Ortholog:

GeneID: 1385 Symbol (Name): CREB1 (cAMP responsive element binding protein 1)

Ortholog Status:

The human GeneID 1385 is also in human dataset(s).

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Caws1/Alcw5	Chronic Alcohol Withdrawal	1		28-47 (cM)	6.5	3.00E-07	Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_009952.2	NP_034082.1	NC_000067.5 range: 64579377..64651121
NM_133828.2	NP_598589.2	NC_000067.5 range: 64579377..64651121

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005667	transcription factor complex	Cellular Component	IDA (11354513)
GO:0005634	nucleus	Cellular Component	IDA (7565774\|14517290\|15817708\|16251435)
GO:0005634	nucleus	Cellular Component	ISS (8798441)
GO:0003677	DNA binding	Molecular Function	IDA (11354513\|14594818)
GO:0043565	sequence-specific DNA binding	Molecular Function	IEA
GO:0046983	protein dimerization activity	Molecular Function	IEA
GO:0005515	protein binding	Molecular Function	IEA
GO:0003700	transcription factor activity	Molecular Function	IDA (12220541)
GO:0003700	transcription factor activity	Molecular Function	ISS (8798441)
GO:0046887	positive regulation of hormone secretion	Biological Process	IMP (16141355)
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	Biological Process	ISS (8798441)
GO:0042493	response to drug	Biological Process	IDA (9098922)
GO:0040018	positive regulation of multicellular organism growth	Biological Process	IMP (16141355)
GO:0030879	mammary gland development	Biological Process	IMP (16141355)
GO:0021983	pituitary gland development	Biological Process	IMP (16141355)
GO:0010033	response to organic substance	Biological Process	ISS (8798441)
GO:0008361	regulation of cell size	Biological Process	IGI (12015964)
GO:0007409	axonogenesis	Biological Process	IMP (11988169)
GO:0006468	protein amino acid phosphorylation	Biological Process	ISS (8798441)
GO:0006355	regulation of transcription, DNA-dependent	Biological Process	IDA (12220541)
GO:0006350	transcription	Biological Process	IEA
GO:0007595	lactation	Biological Process	IMP (16141355)