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Gene Information
Gene ID:13
Symbol:AADAC
Full Name:arylacetamide deacetylase (esterase)
Alias:CES5A1|DAC
Organism:Homo sapiens (Human)
Chromosome:3
Genetic Location:3q21.3-q25.2
Physical Location:153014550-153028965 on NC_000003.10
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:N99791
Fold Change:0.69
P Value:0.02
Tissue:Prefrontal cortex
Dataset Information
Name:15816859
Method:Microarray
Tissue:Prefrontal cortex and nucleus accumbens
Phenotype:Alcohol dependence (AD)/Alcohol abuse/Alcoholism
Publication:Flatscher-Bader et al. J Neurochem.(2005) Alcohol-responsive genes in the frontal cortex and nucleus accumbens of human alcoholics. PubMed
Summary:Genes with a mean fold change > 1.5 or < 0.7 were selected and annotated. Values are taken from microarray analysis and represent mean ratios of alcoholic cases compared with matched control cases(n = 6). P values were from t-test.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_001086.2NP_001077.2NC_000003.10 range: 153014550..153028965
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005783endoplasmic reticulumCellular ComponentIEA
GO:0005789endoplasmic reticulum membraneCellular ComponentIDA (10318829|15152005)
GO:0005792microsomeCellular ComponentTAS (8063807)
GO:0016020membraneCellular ComponentIEA
GO:0016021integral to membraneCellular ComponentIEA
GO:0016298lipase activityMolecular FunctionTAS (11481320)
GO:0019213deacetylase activityMolecular FunctionIDA (9665742)
GO:0008152metabolic processBiological ProcessIEA
Other Database Cross Links
NCBI Entrez Gene:13
HGNC:17
Ensembl:ENSG00000114771
MIM:600338
HPRD:02640
HuGE Navigator:13
dbSNP:AADAC
GeneCard:AADAC
AceView:AADAC