ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Csrp1

Full Name:

cysteine and glycine-rich protein 1

Alias:

AA408841|AA959891|AW545626|CRP1|Csrp

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

1 E4

Physical Location:

137625773-137648805 on NC_000067.5

Gene Type:

protein-coding

Human Ortholog:

GeneID: 1465 Symbol (Name): CSRP1 (cysteine and glycine-rich protein 1)

Ortholog Status:

The human GeneID 1465 is also in human dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

Csrp1

Dataset Information

Name:		16618939
Method:		Microarray
Tissue:		Whole brain
Phenotype:		Alcohol preference
Publication:		Mulligan et al. Proc Natl Acad Sci U S A. (2006) Toward understanding the genetics of alcohol drinking through transcriptome meta-analysis. PubMed
Summary:		Microarray analyses of brain gene expression in three selected lines, and six isogenic strains of mice known to differ markedly in voluntary alcohol consumption provided >4.5 million data points for a meta-analysis. A total of 107 arrays were obtained and arranged into six experimental data sets, allowing the identification of 3,800 unique genes significantly and consistently changed between all models of high or low amounts of alcohol consumption. Here we select the 75 genes with the largest effect size (\|d\|) and lowest Q values.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_007791.5	NP_031817.1	NC_000067.5 range: 137625773..137648805

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005634	nucleus	Cellular Component	RCA (12466851)
GO:0015629	actin cytoskeleton	Cellular Component	TAS (10090149)
GO:0005515	protein binding	Molecular Function	IPI (10926853)
GO:0008270	zinc ion binding	Molecular Function	RCA (12466851)
GO:0046872	metal ion binding	Molecular Function	IEA
GO:0030036	actin cytoskeleton organization and biogenesis	Biological Process	TAS (10090149)