ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Cyp2d10

Full Name:

cytochrome P450, family 2, subfamily d, polypeptide 10

Alias:

AI303445|Cyp2d|P450-2D

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

15 E1|15 47.2 cM

Physical Location:

82233275-82237610 on NC_000081.5, complement

Gene Type:

protein-coding

Human Ortholog:

This gene has no human ortholog.

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Lore5	Alcohol-induced Loss of Righting Reflex	15		18.8-61.7 (cM)	4		Significant	PARC
Aaq1/Etacc	Alcohol Acceptance	15	30	15-48 (cM)	3.8		Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_010005.2	NP_034135.2	NC_000081.5 range: 82233275..82237610, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0016021	integral to membrane	Cellular Component	RCA (12466851)
GO:0005783	endoplasmic reticulum	Cellular Component	IEA
GO:0005792	microsome	Cellular Component	IEA
GO:0016020	membrane	Cellular Component	IEA
GO:0046872	metal ion binding	Molecular Function	IEA
GO:0020037	heme binding	Molecular Function	IEA
GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	Molecular Function	IEA
GO:0016491	oxidoreductase activity	Molecular Function	IEA
GO:0004497	monooxygenase activity	Molecular Function	IEA
GO:0009055	electron carrier activity	Molecular Function	IEA
GO:0005506	iron ion binding	Molecular Function	IEA
GO:0050381	unspecific monooxygenase activity	Molecular Function	IEA