ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Dlx2

Full Name:

distal-less homeobox 2

Alias:

AW121999|Dlx-2|Tes-1

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

2 C2|2 44.0 cM

Physical Location:

71381465-71384797 on NC_000068.6, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 1746 Symbol (Name): DLX2 (distal-less homeobox 2)

Ortholog Status:

The human GeneID 1746 is not in current human dataset.

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Etact1	Alcohol Stimulated Activity	2	51	41-61 (cM)	3.9	2.20E-05	Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_010054.2	NP_034184.1	NC_000068.6 range: 71381465..71384797, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005634	nucleus	Cellular Component	IDA (12397111\|12724837)
GO:0003677	DNA binding	Molecular Function	IDA (9415433\|14769946)
GO:0003682	chromatin binding	Molecular Function	IDA (14769946)
GO:0003700	transcription factor activity	Molecular Function	IEA
GO:0003727	single-stranded RNA binding	Molecular Function	IPI (16705037)
GO:0005515	protein binding	Molecular Function	IPI (11675124)
GO:0043565	sequence-specific DNA binding	Molecular Function	IEA
GO:0045449	regulation of transcription	Biological Process	IEA
GO:0030154	cell differentiation	Biological Process	IMP (12397111)
GO:0007275	multicellular organismal development	Biological Process	IEA
GO:0006355	regulation of transcription, DNA-dependent	Biological Process	IEA
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	Biological Process	IGI (16705037)