ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Dmc1

Full Name:

DMC1 dosage suppressor of mck1 homolog, meiosis-specific homologous recombination (yeast)disrupted meiotic cDNA 1

Alias:

Dmc1h|MGC151144|Mei11|sgdp

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

15 E|15 47.5 cM

Physical Location:

79391929-79435513 on NC_000081.5, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 11144 Symbol (Name): DMC1 (DMC1 dosage suppressor of mck1 homolog, meiosis-specific homologous recombination (yeast))

Ortholog Status:

The human GeneID 11144 is also in human dataset(s).

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Lore5	Alcohol-induced Loss of Righting Reflex	15		18.8-61.7 (cM)	4		Significant	PARC
Aaq1/Etacc	Alcohol Acceptance	15	30	15-48 (cM)	3.8		Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_010059.2	NP_034189.1	NC_000081.5 range: 79391929..79435513, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005622	intracellular	Cellular Component	IEA
GO:0005634	nucleus	Cellular Component	IEA
GO:0000166	nucleotide binding	Molecular Function	IEA
GO:0017111	nucleoside-triphosphatase activity	Molecular Function	IEA
GO:0008094	DNA-dependent ATPase activity	Molecular Function	IEA
GO:0043565	sequence-specific DNA binding	Molecular Function	IEA
GO:0005524	ATP binding	Molecular Function	IEA
GO:0003677	DNA binding	Molecular Function	IEA
GO:0006259	DNA metabolic process	Biological Process	IEA
GO:0007126	meiosis	Biological Process	IEA
GO:0007131	meiotic recombination	Biological Process	IEA
GO:0007276	gamete generation	Biological Process	IMP (12855593)
GO:0007283	spermatogenesis	Biological Process	IMP (12855593)
GO:0001541	ovarian follicle development	Biological Process	IMP (15640358)
GO:0007049	cell cycle	Biological Process	IEA