ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Dnase2a

Full Name:

deoxyribonuclease II alpha

Alias:

Dnase2

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

8 C3|8 38.6 cM

Physical Location:

87432522-87435359 on NC_000074.5

Gene Type:

protein-coding

Human Ortholog:

GeneID: 1777 Symbol (Name): DNASE2 (deoxyribonuclease II, lysosomal)

Ortholog Status:

The human GeneID 1777 is not in current human dataset.

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Caws3/Alcw6	Chronic Alcohol Withdrawal	8		16-43 (cM)	3.5	0.0003	Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_010062.3	NP_034192.1	NC_000074.5 range: 87432522..87435359

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005615	extracellular space	Cellular Component	RCA (12466851)
GO:0005764	lysosome	Cellular Component	TAS (11375492)
GO:0004518	nuclease activity	Molecular Function	IEA
GO:0004519	endonuclease activity	Molecular Function	IEA
GO:0004531	deoxyribonuclease II activity	Molecular Function	IDA (11375492)
GO:0016787	hydrolase activity	Molecular Function	IEA
GO:0007275	multicellular organismal development	Biological Process	IEA
GO:0006915	apoptosis	Biological Process	IEA
GO:0006308	DNA catabolic process	Biological Process	IMP (15568025)
GO:0006259	DNA metabolic process	Biological Process	IEA
GO:0030218	erythrocyte differentiation	Biological Process	IMP (11375492)