ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Adam28

Full Name:

a disintegrin and metallopeptidase domain 28

Alias:

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

14 D2

Physical Location:

69224083-69273898 on NC_000080.5, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 10863 Symbol (Name): ADAM28 (ADAM metallopeptidase domain 28)

Ortholog Status:

The human GeneID 10863 is not in current human dataset.

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Caws5/Alcw7	Chronic Alcohol Withdrawal	14		24-48 (cM)	4.2	6.00E-05	Significant	PARC

Gene Refseq Sequence Annotation

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005576	extracellular region	Cellular Component	IEA
GO:0005578	proteinaceous extracellular matrix	Cellular Component	IEA
GO:0005886	plasma membrane	Cellular Component	IDA (15883027)
GO:0016021	integral to membrane	Cellular Component	IEA
GO:0016020	membrane	Cellular Component	IEA
GO:0004222	metalloendopeptidase activity	Molecular Function	IEA
GO:0016787	hydrolase activity	Molecular Function	IEA
GO:0008270	zinc ion binding	Molecular Function	IEA
GO:0008237	metallopeptidase activity	Molecular Function	IEA
GO:0008233	peptidase activity	Molecular Function	IEA
GO:0046872	metal ion binding	Molecular Function	IEA
GO:0007229	integrin-mediated signaling pathway	Biological Process	IEA
GO:0006508	proteolysis	Biological Process	IEA