ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Emx2

Full Name:

empty spiracles homolog 2 (Drosophila)

Alias:

Pdo

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

19 D3|19 53.5 cM

Physical Location:

59533179-59539846 on NC_000085.5

Gene Type:

protein-coding

Human Ortholog:

GeneID: 2018 Symbol (Name): EMX2 (empty spiracles homeobox 2)

Ortholog Status:

The human GeneID 2018 is also in human dataset(s).

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Calw2/Alcdp2	Chronic Alcohol Withdrawal	19	47	36.5-ter (cM)	5.3	6.00E-07	Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_010132.2	NP_034262.2	NC_000085.5 range: 59533179..59539846

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005634	nucleus	Cellular Component	IEA
GO:0003677	DNA binding	Molecular Function	IEA
GO:0003700	transcription factor activity	Molecular Function	IEA
GO:0043565	sequence-specific DNA binding	Molecular Function	IEA
GO:0042493	response to drug	Biological Process	IDA (9098922)
GO:0030900	forebrain development	Biological Process	IMP (15294144)
GO:0030900	forebrain development	Biological Process	IGI (15917450)
GO:0030182	neuron differentiation	Biological Process	IMP (12561075)
GO:0021885	forebrain cell migration	Biological Process	IMP (10729342)
GO:0021846	cell proliferation in forebrain	Biological Process	IMP (10729342)
GO:0021542	dentate gyrus development	Biological Process	IMP (10729342)
GO:0009952	anterior/posterior pattern formation	Biological Process	IMP (12196586)
GO:0009952	anterior/posterior pattern formation	Biological Process	IGI (15917450)
GO:0007420	brain development	Biological Process	IMP (12091317\|12196586\|12209834\|12561075)
GO:0007275	multicellular organismal development	Biological Process	IEA
GO:0006355	regulation of transcription, DNA-dependent	Biological Process	IEA
GO:0045449	regulation of transcription	Biological Process	IEA