ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

En1

Full Name:

engrailed 1

Alias:

En-1|Mo-en.1

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

1 C2-qter|1 64.1 cM

Physical Location:

122499257-122504547 on NC_000067.5

Gene Type:

protein-coding

Human Ortholog:

GeneID: 2019 Symbol (Name): EN1 (engrailed homeobox 1)

Ortholog Status:

The human GeneID 2019 is not in current human dataset.

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Ap1q	Alcohol Preference Drinking	1	76	45-95 (cM)	4.5		Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_010133.2	NP_034263.2	NC_000067.5 range: 122499257..122504547

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005634	nucleus	Cellular Component	IEA
GO:0008076	voltage-gated potassium channel complex	Cellular Component	IEA
GO:0003677	DNA binding	Molecular Function	IEA
GO:0003700	transcription factor activity	Molecular Function	IEA
GO:0005249	voltage-gated potassium channel activity	Molecular Function	IEA
GO:0043565	sequence-specific DNA binding	Molecular Function	IEA
GO:0030902	hindbrain development	Biological Process	IGI (15607945)
GO:0030917	midbrain-hindbrain boundary development	Biological Process	IMP (15607945)
GO:0035115	embryonic forelimb morphogenesis	Biological Process	IGI (9362463)
GO:0043473	pigmentation	Biological Process	IMP (9362463)
GO:0045449	regulation of transcription	Biological Process	IEA
GO:0030901	midbrain development	Biological Process	IGI (15175251\|15607945)
GO:0030326	embryonic limb morphogenesis	Biological Process	IMP (8684466)
GO:0030326	embryonic limb morphogenesis	Biological Process	IGI (15242796)
GO:0030182	neuron differentiation	Biological Process	IGI (15175251\|15340832\|15607945)
GO:0009954	proximal/distal pattern formation	Biological Process	IMP (8684466\|9362463)
GO:0009953	dorsal/ventral pattern formation	Biological Process	IMP (8684466\|9362463)
GO:0007275	multicellular organismal development	Biological Process	IEA
GO:0006813	potassium ion transport	Biological Process	IEA
GO:0006355	regulation of transcription, DNA-dependent	Biological Process	IEA
GO:0048666	neuron development	Biological Process	IGI (11312297)