ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Epha2

Full Name:

Eph receptor A2

Alias:

AW545284|Eck|Myk2|Sek-2|Sek2

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

4 D-E|4 73.2 cM

Physical Location:

140857154-140885292 on NC_000070.5

Gene Type:

protein-coding

Human Ortholog:

GeneID: 1969 Symbol (Name): EPHA2 (EPH receptor A2)

Ortholog Status:

The human GeneID 1969 is not in current human dataset.

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Ap3q	Alcohol Preference Drinking	4	75	65-ter (cM)	4.6		Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_010139.2	NP_034269.2	NC_000070.5 range: 140857154..140885292

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005615	extracellular space	Cellular Component	RCA (12466851)
GO:0016021	integral to membrane	Cellular Component	RCA (12466851)
GO:0016020	membrane	Cellular Component	IEA
GO:0016301	kinase activity	Molecular Function	IEA
GO:0000166	nucleotide binding	Molecular Function	IEA
GO:0005524	ATP binding	Molecular Function	IEA
GO:0005003	ephrin receptor activity	Molecular Function	IEA
GO:0004872	receptor activity	Molecular Function	IEA
GO:0004714	transmembrane receptor protein tyrosine kinase activity	Molecular Function	IEA
GO:0004713	protein-tyrosine kinase activity	Molecular Function	IEA
GO:0004672	protein kinase activity	Molecular Function	IEA
GO:0016740	transferase activity	Molecular Function	IEA
GO:0030182	neuron differentiation	Biological Process	IMP (15145949)
GO:0030182	neuron differentiation	Biological Process	IDA (15145949)
GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway	Biological Process	IEA
GO:0006468	protein amino acid phosphorylation	Biological Process	IEA
GO:0048013	ephrin receptor signaling pathway	Biological Process	IDA (14988728)