ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Epha4

Full Name:

Eph receptor A4

Alias:

2900005C20Rik|AI385584|Cek8|Hek8|Sek|Sek1|Tyro1|rb

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

1 C1-C5|1 43.0 cM

Physical Location:

77363759-77511662 on NC_000067.5, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 2043 Symbol (Name): EPHA4 (EPH receptor A4)

Ortholog Status:

The human GeneID 2043 is not in current human dataset.

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Caws1/Alcw5	Chronic Alcohol Withdrawal	1		28-47 (cM)	6.5	3.00E-07	Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_007936.3	NP_031962.2	NC_000067.5 range: 77363759..77511662, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0016021	integral to membrane	Cellular Component	RCA (12466851)
GO:0016020	membrane	Cellular Component	IEA
GO:0000166	nucleotide binding	Molecular Function	IEA
GO:0016301	kinase activity	Molecular Function	IEA
GO:0016740	transferase activity	Molecular Function	IEA
GO:0005524	ATP binding	Molecular Function	IEA
GO:0005515	protein binding	Molecular Function	IPI (17719550)
GO:0005003	ephrin receptor activity	Molecular Function	IEA
GO:0004872	receptor activity	Molecular Function	IEA
GO:0004714	transmembrane receptor protein tyrosine kinase activity	Molecular Function	IEA
GO:0004713	protein-tyrosine kinase activity	Molecular Function	IEA
GO:0004672	protein kinase activity	Molecular Function	IEA
GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway	Biological Process	IEA
GO:0007411	axon guidance	Biological Process	IMP (12649481)
GO:0007628	adult walking behavior	Biological Process	IMP (12649481)
GO:0006468	protein amino acid phosphorylation	Biological Process	IEA