ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

13844

Symbol:

Ephb2

Full Name:

Eph receptor B2

Alias:

Cek5|Drt|ETECK|Erk|Hek5|Nuk|Prkm5|Qek5|Sek3|Tyro5

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

4 D-E|4 65.7 cM

Physical Location:

136209522-136391849 on NC_000070.5, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 2048 Symbol (Name): EPHB2 (EPH receptor B2)

Ortholog Status:

The human GeneID 2048 is not in current human dataset.

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Ap3q	Alcohol Preference Drinking	4	75	65-ter (cM)	4.6		Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_010142.2	NP_034272.1	NC_000070.5 range: 136209522..136391849, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0016021	integral to membrane	Cellular Component	IEA
GO:0016020	membrane	Cellular Component	IEA
GO:0045202	synapse	Cellular Component	NAS (9883737)
GO:0005887	integral to plasma membrane	Cellular Component	TAS (11532925)
GO:0016301	kinase activity	Molecular Function	IEA
GO:0008046	axon guidance receptor activity	Molecular Function	IDA (11532925)
GO:0016740	transferase activity	Molecular Function	IEA
GO:0005524	ATP binding	Molecular Function	IEA
GO:0005515	protein binding	Molecular Function	IPI (11754835\|11780069)
GO:0005102	receptor binding	Molecular Function	IDA (11754835)
GO:0004672	protein kinase activity	Molecular Function	IEA
GO:0004713	protein-tyrosine kinase activity	Molecular Function	IEA
GO:0004714	transmembrane receptor protein tyrosine kinase activity	Molecular Function	IEA
GO:0004872	receptor activity	Molecular Function	IEA
GO:0005003	ephrin receptor activity	Molecular Function	IDA (11780069)
GO:0005005	transmembrane-ephrin receptor activity	Molecular Function	TAS (11532925)
GO:0000166	nucleotide binding	Molecular Function	IEA
GO:0048168	regulation of neuronal synaptic plasticity	Biological Process	IMP (11754835)
GO:0048170	positive regulation of long-term neuronal synaptic plasticity	Biological Process	IMP (11754836)
GO:0009887	organ morphogenesis	Biological Process	IMP (15223334)
GO:0007612	learning	Biological Process	IMP (11754835)
GO:0007411	axon guidance	Biological Process	IDA (11532925)
GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway	Biological Process	IDA (14988728)
GO:0006468	protein amino acid phosphorylation	Biological Process	IEA
GO:0050770	regulation of axonogenesis	Biological Process	IDA (14988728)