ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Esd

Full Name:

esterase D/formylglutathione hydrolase

Alias:

Es-10|Es10|sid478

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

14 D2-E2|14 41.5 cM

Physical Location:

75132151-75150249 on NC_000080.5

Gene Type:

protein-coding

Human Ortholog:

GeneID: 2098 Symbol (Name): ESD (esterase D/formylglutathione hydrolase)

Ortholog Status:

The human GeneID 2098 is also in human dataset(s).

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Caws5/Alcw7	Chronic Alcohol Withdrawal	14		24-48 (cM)	4.2	6.00E-05	Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_016903.4	NP_058599.1	NC_000080.5 range: 75132151..75150249

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005737	cytoplasm	Cellular Component	IEA
GO:0016023	cytoplasmic membrane-bounded vesicle	Cellular Component	RCA (12466851)
GO:0031410	cytoplasmic vesicle	Cellular Component	IEA
GO:0003824	catalytic activity	Molecular Function	RCA (12466851)
GO:0004091	carboxylesterase activity	Molecular Function	RCA (12466851)
GO:0016787	hydrolase activity	Molecular Function	RCA (12466851)
GO:0016788	hydrolase activity, acting on ester bonds	Molecular Function	IDA (869894\|1914521\|7323947\|7444718)
GO:0018738	S-formylglutathione hydrolase activity	Molecular Function	IEA