ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Ext1

Full Name:

exostoses (multiple) 1

Alias:

AA409028

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

15 C|15 26.55 cM

Physical Location:

52899815-53177737 on NC_000081.5, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 2131 Symbol (Name): EXT1 (exostoses (multiple) 1)

Ortholog Status:

The human GeneID 2131 is not in current human dataset.

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Lore5	Alcohol-induced Loss of Righting Reflex	15		18.8-61.7 (cM)	4		Significant	PARC
Aaq1/Etacc	Alcohol Acceptance	15	30	15-48 (cM)	3.8		Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_010162.2	NP_034292.2	NC_000081.5 range: 52899815..53177737, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005615	extracellular space	Cellular Component	RCA (12466851)
GO:0030176	integral to endoplasmic reticulum membrane	Cellular Component	IDA (9620772)
GO:0016021	integral to membrane	Cellular Component	IEA
GO:0016020	membrane	Cellular Component	IEA
GO:0005783	endoplasmic reticulum	Cellular Component	IEA
GO:0005794	Golgi apparatus	Cellular Component	IEA
GO:0050509	N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity	Molecular Function	IDA (10639137)
GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity	Molecular Function	IDA (10639137)
GO:0016757	transferase activity, transferring glycosyl groups	Molecular Function	IEA
GO:0016740	transferase activity	Molecular Function	IEA
GO:0007369	gastrulation	Biological Process	IMP (10926768)
GO:0015012	heparan sulfate proteoglycan biosynthetic process	Biological Process	IDA (10639137)
GO:0007498	mesoderm development	Biological Process	IMP (10926768)
GO:0007492	endoderm development	Biological Process	IMP (10926768)