| Gene Information |
| Gene ID: | | 140559 |
| Symbol: | | Igsf8 |
| Full Name: | | immunoglobulin superfamily, member 8 |
| Alias: | | AA033172|AU041109|ESTM34|EWI-2|KCT-4|PGRL|R75384 |
| Organism: | | Mus musculus (Mouse) |
| Chromosome: | | 1 |
| Genetic Location: | | 1 H3|1 94.2 cM |
| Physical Location: | | 174242537-174249967 on NC_000067.5 |
| Gene Type: | | protein-coding |
| Human Ortholog: | | GeneID: 93185 Symbol (Name): IGSF8 (immunoglobulin superfamily, member 8) |
| Ortholog Status: | | The human GeneID 93185 is not in current human dataset. |
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| Gene in Ethanol Study Datasets |
| Gene Information | | | Dataset Information | | Name: | | 16618939 | | Method: | | Microarray | | Tissue: | | Whole brain | | Phenotype: | | Alcohol preference | | Publication: | | Mulligan et al. Proc Natl Acad Sci U S A. (2006) Toward understanding the genetics of alcohol drinking through transcriptome meta-analysis. PubMed | | Summary: | | Microarray analyses of brain gene expression in three selected lines, and six isogenic strains of mice known to differ markedly in voluntary alcohol consumption provided >4.5 million data points for a meta-analysis. A total of 107 arrays were obtained and arranged into six experimental data sets, allowing the identification of 3,800 unique genes significantly and consistently changed between all models of high or low amounts of alcohol consumption. Here we select the 75 genes with the largest effect size (|d|) and lowest Q values. |
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| QTL Information | | QTL | Phenotype | Chr | Peak (cM) | LOD | P Value | Range | Status | QTL Link | |
| Alcw1 | Acute Alcohol Withdrawal | 1 | 96 | 172.3-176.5 (Mb) | 5.6 | 3.00E-07 | Significant | PARC | | Calw1/Alcdp1 | Chronic Alcohol Withdrawal | 1 | 96 | 89-106.3 (cM) | 7.6 | 2.00E-09 | Significant | PARC | | Ap1q | Alcohol Preference Drinking | 1 | 76 | 45-95 (cM) | 4.5 | | Significant | PARC |
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| Gene Refseq Sequence Annotation |
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| Gene Ontology (GO) Annotation |
| GO ID | GO Term | Category | Evidence (PubMed) | |
| GO:0005615 | extracellular space | Cellular Component | RCA (12466851) | |
| GO:0016020 | membrane | Cellular Component | IEA | |
| GO:0016021 | integral to membrane | Cellular Component | ISS (11504738) | |
| GO:0016021 | integral to membrane | Cellular Component | RCA (12466851) | |
| GO:0005515 | protein binding | Molecular Function | IDA (11504738) | |
| GO:0008150 | biological_process | Biological Process | ND | |
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| Other Database Cross Links |
| NCBI Entrez Gene: | | 140559 |
| MGI: | |
| Ensembl: | | ENSMUSG00000038034 |
| dbSNP: | | Igsf8 |
| AceView: | | Igsf8 |
