ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Full Name:

coagulation factor II

Alias:

Cf-2|Cf2|FII

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

2 E1|2 47.5 cM

Physical Location:

91465476-91476570 on NC_000068.6, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 2147 Symbol (Name): F2 (coagulation factor II (thrombin))

Ortholog Status:

The human GeneID 2147 is not in current human dataset.

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Etact1	Alcohol Stimulated Activity	2	51	41-61 (cM)	3.9	2.20E-05	Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_010168.2	NP_034298.1	NC_000068.6 range: 91465476..91476570, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005576	extracellular region	Cellular Component	IEA
GO:0005615	extracellular space	Cellular Component	RCA (12466851)
GO:0003809	thrombin activity	Molecular Function	IEA
GO:0004252	serine-type endopeptidase activity	Molecular Function	IEA
GO:0005509	calcium ion binding	Molecular Function	IEA
GO:0016787	hydrolase activity	Molecular Function	IEA
GO:0008233	peptidase activity	Molecular Function	IEA
GO:0007596	blood coagulation	Biological Process	IEA
GO:0006953	acute-phase response	Biological Process	IEA
GO:0006508	proteolysis	Biological Process	IEA
GO:0030168	platelet activation	Biological Process	IDA (17380206)