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Gene Information
Gene ID:140739
Symbol:UBE2F
Full Name:ubiquitin-conjugating enzyme E2F (putative)
Alias:MGC18120|NCE2
Organism:Homo sapiens (Human)
Chromosome:2
Genetic Location:2q37.3
Physical Location:238540438-238615422 on NC_000002.10
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Linkage Dataset
MarkerLODP valueLocation (bp)
D2S29732.200.0007235696080
D2S1401.950.0014241388318
Region:235696080-241388318
Phenotype:WDSFS (withdrawal symptoms factor score)
Name:17067344
Method:Linkage
Publication:Kuo et al. Alcohol Clin Exp Res. (2006) Identification of susceptibility loci for alcohol-related traits in the Irish Affected Sib Pair Study of Alcohol Dependence. PubMed
Summary:A 4-cM dense whole-genome linkage study was conducted in the Irish Affected Sib Pair Study of Alcohol Dependence. Probands, affected siblings, and parents were evaluated by structured interview. Variance component linkage analysis was applied to data from 485 families for 5 measures: initial sensitivity and tolerance (based on scales from the self-report of the effects of ethanol; maximum drinks within 24 hours, an empirically derived factor score based on withdrawal symptoms, and age at onset of alcohol dependence.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_080678.1NP_542409.1NC_000002.10 range: 238540438..238615422
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0016874ligase activityMolecular FunctionIEA
GO:0019787small conjugating protein ligase activityMolecular FunctionIEA
GO:0006512ubiquitin cycleBiological ProcessIEA
GO:0051246regulation of protein metabolic processBiological ProcessIEA
Other Database Cross Links
NCBI Entrez Gene:140739
HGNC:12480
Ensembl:ENSG00000184182
MIM:
HPRD:14812
HuGE Navigator:140739
dbSNP:UBE2F
GeneCard:UBE2F
AceView:UBE2F