| Gene Information |
| Gene ID: | | 140742 |
| Symbol: | | Sesn1 |
| Full Name: | | sestrin 1 |
| Alias: | | 1110002G11Rik|AU044290|MGC118148|PA26|SEST1 |
| Organism: | | Mus musculus (Mouse) |
| Chromosome: | | 10 |
| Genetic Location: | | 10 B2|10 25.0 cM |
| Physical Location: | | 41607254-41628229 on NC_000076.5 |
| Gene Type: | | protein-coding |
| Human Ortholog: | | GeneID: 27244 Symbol (Name): SESN1 (sestrin 1) |
| Ortholog Status: | | The human GeneID 27244 is not in current human dataset. |
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| Gene in Ethanol Study Datasets |
| Gene Information | | Original ID1: | | AI843106 | | Fold Change: | | 1.6, 1.6, 1.7, 1.4 | | Note: | | 4 fold changes are from C57BL/6J trial 1, C57BL/6J trial 2, DBA/2J trial 1, DBA/2J trial 2 |
| | Dataset Information | | Name: | | 15002731 | | Method: | | Microarray | | Tissue: | | Whole brain | | Phenotype: | | Acute ethanol response | | Publication: | | Treadwell et al. Neurochem Res. (2004) Microarray analysis of mouse brain gene expression following acute ethanol treatment. PubMed | | Summary: | | We have analyzed the expression of approximately 24,000 genes using oligonucleotide microarrays to examine the brain expression profiles in two strains of inbred mice, C57BL/6J and DBA/2J, following exposure to an acute dose of ethanol. Our screen identified 61 genes responding to the ethanol treatment beyond a 1.5-fold threshold, with 46 genes altered in both mouse strains and 15 altered in only one strain. |
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| Gene Refseq Sequence Annotation |
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| Gene Ontology (GO) Annotation |
| GO ID | GO Term | Category | Evidence (PubMed) | |
| GO:0005634 | nucleus | Cellular Component | IEA | |
| GO:0007050 | cell cycle arrest | Biological Process | IEA | |
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| Other Database Cross Links |
| NCBI Entrez Gene: | | 140742 |
| MGI: | |
| Ensembl: | | ENSMUSG00000038332 |
| dbSNP: | | Sesn1 |
| AceView: | | Sesn1 |
