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Gene Information
Gene ID:140742
Symbol:Sesn1
Full Name:sestrin 1
Alias:1110002G11Rik|AU044290|MGC118148|PA26|SEST1
Organism:Mus musculus (Mouse)
Chromosome:10
Genetic Location:10 B2|10 25.0 cM
Physical Location:41607254-41628229 on NC_000076.5
Gene Type:protein-coding
Human Ortholog:GeneID: 27244    Symbol (Name): SESN1 (sestrin 1)
Ortholog Status:The human GeneID 27244 is not in current human dataset.
Gene in Ethanol Study Datasets
Gene Information
Original ID1:AI843106
Fold Change:1.6, 1.6, 1.7, 1.4
Note:4 fold changes are from C57BL/6J trial 1, C57BL/6J trial 2, DBA/2J trial 1, DBA/2J trial 2
Dataset Information
Name:15002731
Method:Microarray
Tissue:Whole brain
Phenotype:Acute ethanol response
Publication:Treadwell et al. Neurochem Res. (2004) Microarray analysis of mouse brain gene expression following acute ethanol treatment. PubMed
Summary:We have analyzed the expression of approximately 24,000 genes using oligonucleotide microarrays to examine the brain expression profiles in two strains of inbred mice, C57BL/6J and DBA/2J, following exposure to an acute dose of ethanol. Our screen identified 61 genes responding to the ethanol treatment beyond a 1.5-fold threshold, with 46 genes altered in both mouse strains and 15 altered in only one strain.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_001013370.1NP_001013388.1NC_000076.5 range: 41607254..41628229
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005634nucleusCellular ComponentIEA
GO:0007050cell cycle arrestBiological ProcessIEA
Other Database Cross Links
NCBI Entrez Gene:140742
MGI:
Ensembl:ENSMUSG00000038332
dbSNP:Sesn1
AceView:Sesn1