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Gene Information
Gene ID:140775
Symbol:SMCR8
Full Name:Smith-Magenis syndrome chromosome region, candidate 8
Alias:FLJ34716
Organism:Homo sapiens (Human)
Chromosome:17
Genetic Location:17p11.2
Physical Location:18159318-18172094 on NC_000017.9
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Linkage Dataset
MarkerLODP valueLocation (bp)
D17S1857  16355942
Region:14355942-18355942
Phenotype:Alcoholism phenotype along with age, gender, and P300 or constraint
Name:15211641
Method:Linkage
Publication:Hill et al. Am J Med Genet B Neuropsychiatr Genet. (2004) A genome wide search for alcoholism susceptibility genes. PubMed
Summary:A total of 360 markers for 22 autosomes were spaced at an average distance of 9.4cMand genotyping performed for 330 members of these multiplex families. Extensive clinical data, personality variation, and event-related potential characteristics were available for reducing heterogeneity and detecting robust linkage signals. Multipoint linkage analysis using different analytic strategies give strong support for loci on chromosomes 1, 2, 6, 7, 10, 12, 14, 16, and 17. Thirty five markers with LOD score >2.0 at baseline using the binary alcoholism phenotype along with age, gender, and P300 or constraint (Table III). Here we listed the genes between two near markers or genes near a separate marker (within 2Mb).
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_144775.2NP_658988.2NC_000017.9 range: 18159318..18172094
Other Database Cross Links
NCBI Entrez Gene:140775
HGNC:17921
Ensembl:ENSG00000176994
MIM:
HPRD:18075
HuGE Navigator:140775
dbSNP:SMCR8
GeneCard:SMCR8
AceView:SMCR8