ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Fasl

Full Name:

Fas ligand (TNF superfamily, member 6)

Alias:

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

1 H2.1|1 85.0 cM

Physical Location:

163710819-163718625 on NC_000067.5, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 356 Symbol (Name): FASLG (Fas ligand (TNF superfamily, member 6))

Ortholog Status:

The human GeneID 356 is not in current human dataset.

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Ap1q	Alcohol Preference Drinking	1	76	45-95 (cM)	4.5		Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_010177.3	NP_034307.1	NC_000067.5 range: 163710819..163718625, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005576	extracellular region	Cellular Component	IEA
GO:0005615	extracellular space	Cellular Component	IEA
GO:0016021	integral to membrane	Cellular Component	RCA (12466851)
GO:0016020	membrane	Cellular Component	IEA
GO:0009897	external side of plasma membrane	Cellular Component	IDA (16973387)
GO:0005125	cytokine activity	Molecular Function	IEA
GO:0005164	tumor necrosis factor receptor binding	Molecular Function	IEA
GO:0043065	positive regulation of apoptosis	Biological Process	ISS (14749367)
GO:0043065	positive regulation of apoptosis	Biological Process	IGI (15039234)
GO:0008624	induction of apoptosis by extracellular signals	Biological Process	IDA (7511063\|15039234\|15629131)
GO:0007165	signal transduction	Biological Process	IEA
GO:0006955	immune response	Biological Process	IEA
GO:0006915	apoptosis	Biological Process	IGI (16365167)
GO:0046666	retinal cell programmed cell death	Biological Process	IMP (14517994)