ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

14125

Symbol:

Fcer1a

Full Name:

Fc receptor, IgE, high affinity I, alpha polypeptide

Alias:

FcERI|Fce1a|Fcr-5|fcepsilonri

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

1 H3|1 94.2 cM

Physical Location:

175151414-175157344 on NC_000067.5, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 2205 Symbol (Name): FCER1A (Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide)

Ortholog Status:

The human GeneID 2205 is not in current human dataset.

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Alcw1	Acute Alcohol Withdrawal	1	96	172.3-176.5 (Mb)	5.6	3.00E-07	Significant	PARC
Calw1/Alcdp1	Chronic Alcohol Withdrawal	1	96	89-106.3 (cM)	7.6	2.00E-09	Significant	PARC
Ap1q	Alcohol Preference Drinking	1	76	45-95 (cM)	4.5		Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_010184.1	NP_034314.1	NC_000067.5 range: 175151414..175157344, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0016021	integral to membrane	Cellular Component	IEA
GO:0016020	membrane	Cellular Component	IEA
GO:0009897	external side of plasma membrane	Cellular Component	IDA (2527850\|9000133)
GO:0005887	integral to plasma membrane	Cellular Component	IDA (2527850)
GO:0045121	membrane raft	Cellular Component	TAS (12192036)
GO:0019767	IgE receptor activity	Molecular Function	IMP (8252632)
GO:0019863	IgE binding	Molecular Function	IDA (2527850)
GO:0019863	IgE binding	Molecular Function	IMP (8252632)
GO:0019767	IgE receptor activity	Molecular Function	IDA (9000133)
GO:0004872	receptor activity	Molecular Function	IEA
GO:0045401	positive regulation of interleukin-3 biosynthetic process	Biological Process	IDA (9000133)
GO:0045425	positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process	Biological Process	IDA (9000133)
GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	Biological Process	IDA (9000133)
GO:0043306	positive regulation of mast cell degranulation	Biological Process	IDA (9000133)
GO:0019370	leukotriene biosynthetic process	Biological Process	IDA (9000133)
GO:0001812	positive regulation of type I hypersensitivity	Biological Process	IMP (8252632)
GO:0001820	serotonin secretion	Biological Process	IDA (9000133)
GO:0001820	serotonin secretion	Biological Process	IMP (8252632)
GO:0007165	signal transduction	Biological Process	IDA (12192036)
GO:0007166	cell surface receptor linked signal transduction	Biological Process	IDA (9000133)
GO:0007166	cell surface receptor linked signal transduction	Biological Process	IMP (8252632)
GO:0007257	activation of JNK activity	Biological Process	IDA (9000133)
GO:0000187	activation of MAPK activity	Biological Process	IDA (9000133)
GO:0050850	positive regulation of calcium-mediated signaling	Biological Process	IDA (9000133)