ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Xrcc6

Full Name:

X-ray repair complementing defective repair in Chinese hamster cells 6

Alias:

70kDa|G22p1|Ku70

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

15 E-F|15 47.5 cM

Physical Location:

81846798-81870520 on NC_000081.5

Gene Type:

protein-coding

Human Ortholog:

GeneID: 2547 Symbol (Name): XRCC6 (X-ray repair complementing defective repair in Chinese hamster cells 6 (Ku autoantigen, 70kDa))

Ortholog Status:

The human GeneID 2547 is not in current human dataset.

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Lore5	Alcohol-induced Loss of Righting Reflex	15		18.8-61.7 (cM)	4		Significant	PARC
Aaq1/Etacc	Alcohol Acceptance	15	30	15-48 (cM)	3.8		Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
XM_001479829.1	XP_001479879.1	NC_000081.5 range: 81846798..81870520

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005634	nucleus	Cellular Component	IDA (12604618)
GO:0005737	cytoplasm	Cellular Component	IDA (12604618)
GO:0005958	DNA-dependent protein kinase complex	Cellular Component	IEA
GO:0003676	nucleic acid binding	Molecular Function	IEA
GO:0003677	DNA binding	Molecular Function	IEA
GO:0004003	ATP-dependent DNA helicase activity	Molecular Function	IEA
GO:0033151	V(D)J recombination	Biological Process	IMP (10716994)
GO:0010212	response to ionizing radiation	Biological Process	IMP (15979950)
GO:0006974	response to DNA damage stimulus	Biological Process	IMP (15979950)
GO:0006310	DNA recombination	Biological Process	IEA
GO:0006303	double-strand break repair via nonhomologous end joining	Biological Process	IMP (11751629)
GO:0006302	double-strand break repair	Biological Process	IMP (11751629)
GO:0006281	DNA repair	Biological Process	IEA
GO:0050769	positive regulation of neurogenesis	Biological Process	IMP (10716994)