ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Gabrb2

Full Name:

gamma-aminobutyric acid (GABA-A) receptor, subunit beta 2

Alias:

AI834970|C030002O17Rik|C030021G16Rik|Gabrab2|Gabrb-2

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

11 A5|11 28.6 cM

Physical Location:

42233258-42446092 on NC_000077.5

Gene Type:

protein-coding

Human Ortholog:

GeneID: 2561 Symbol (Name): GABRB2 (gamma-aminobutyric acid (GABA) A receptor, beta 2)

Ortholog Status:

The human GeneID 2561 is also in human dataset(s).

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Caws4/Alcw3	Chronic Alcohol Withdrawal	11		15-36 (cM)	6.7	2.00E-07	Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_008070.3	NP_032096.1	NC_000077.5 range: 42233258..42446092

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0045211	postsynaptic membrane	Cellular Component	IEA
GO:0045202	synapse	Cellular Component	IEA
GO:0030054	cell junction	Cellular Component	IEA
GO:0016021	integral to membrane	Cellular Component	RCA (12466851)
GO:0005615	extracellular space	Cellular Component	RCA (12466851)
GO:0016020	membrane	Cellular Component	RCA (12466851)
GO:0031404	chloride ion binding	Molecular Function	IEA
GO:0030594	neurotransmitter receptor activity	Molecular Function	IEA
GO:0004872	receptor activity	Molecular Function	IEA
GO:0005515	protein binding	Molecular Function	IPI (12574411)
GO:0005254	chloride channel activity	Molecular Function	IEA
GO:0005230	extracellular ligand-gated ion channel activity	Molecular Function	RCA (12466851)
GO:0005216	ion channel activity	Molecular Function	RCA (12466851)
GO:0004890	GABA-A receptor activity	Molecular Function	IEA
GO:0007268	synaptic transmission	Biological Process	RCA (12466851)
GO:0006810	transport	Biological Process	RCA (12466851)
GO:0006811	ion transport	Biological Process	RCA (12466851)