ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Gad1

Full Name:

glutamic acid decarboxylase 1

Alias:

EP10|GAD25|GAD44|GAD67|Gad-1

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

2 D|2 43.0 cM

Physical Location:

70400220-70440068 on NC_000068.6

Gene Type:

protein-coding

Human Ortholog:

GeneID: 2571 Symbol (Name): GAD1 (glutamate decarboxylase 1 (brain, 67kDa))

Ortholog Status:

The human GeneID 2571 is also in human dataset(s).

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Etact1	Alcohol Stimulated Activity	2	51	41-61 (cM)	3.9	2.20E-05	Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_008077.4	NP_032103.2	NC_000068.6 range: 70400220..70440068

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0045202	synapse	Cellular Component	IDA (15479642)
GO:0030424	axon	Cellular Component	IDA (15479642)
GO:0005737	cytoplasm	Cellular Component	IDA (15347806)
GO:0005739	mitochondrion	Cellular Component	IDA (14651853)
GO:0030170	pyridoxal phosphate binding	Molecular Function	IEA
GO:0016831	carboxy-lyase activity	Molecular Function	IEA
GO:0016829	lyase activity	Molecular Function	IEA
GO:0004351	glutamate decarboxylase activity	Molecular Function	IEA
GO:0003824	catalytic activity	Molecular Function	IEA
GO:0019752	carboxylic acid metabolic process	Biological Process	IEA
GO:0007268	synaptic transmission	Biological Process	IEA
GO:0042136	neurotransmitter biosynthetic process	Biological Process	IEA