ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

14463

Symbol:

Gata4

Full Name:

GATA binding protein 4

Alias:

Gata-4

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

14 D1|14 28.0 cM

Physical Location:

63817751-63864096 on NC_000080.5, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 2626 Symbol (Name): GATA4 (GATA binding protein 4)

Ortholog Status:

The human GeneID 2626 is also in human dataset(s).

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Caws5/Alcw7	Chronic Alcohol Withdrawal	14		24-48 (cM)	4.2	6.00E-05	Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_008092.3	NP_032118.2	NC_000080.5 range: 63817751..63864096, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005634	nucleus	Cellular Component	IDA (12130579\|12606418\|15767668\|15830381\|17272516)
GO:0008270	zinc ion binding	Molecular Function	IEA
GO:0030528	transcription regulator activity	Molecular Function	IEA
GO:0016563	transcription activator activity	Molecular Function	IDA (14978031)
GO:0046872	metal ion binding	Molecular Function	IEA
GO:0043565	sequence-specific DNA binding	Molecular Function	IDA (8455608)
GO:0005515	protein binding	Molecular Function	IPI (9621431\|9927675\|11724781\|15525990\|17445768)
GO:0003704	specific RNA polymerase II transcription factor activity	Molecular Function	IDA (8007990\|8455608)
GO:0003702	RNA polymerase II transcription factor activity	Molecular Function	IDA (12606418)
GO:0003700	transcription factor activity	Molecular Function	IDA (9738004\|15082719)
GO:0003677	DNA binding	Molecular Function	ISO
GO:0003677	DNA binding	Molecular Function	IDA (8007990\|9738004\|15539431)
GO:0045893	positive regulation of transcription, DNA-dependent	Biological Process	IDA (14978031)
GO:0048598	embryonic morphogenesis	Biological Process	IMP (9136932\|9136933)
GO:0045941	positive regulation of transcription	Biological Process	IEA
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	Biological Process	IDA (8007990\|8455608\|15539431\|16380715)
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	Biological Process	IGI (15539431\|15766748)
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	Biological Process	IMP (17272516)
GO:0048558	embryonic gut morphogenesis	Biological Process	IMP (16127717)
GO:0035054	embryonic heart tube anterior/posterior pattern formation	Biological Process	IMP (9136932)
GO:0001702	gastrulation with mouth forming second	Biological Process	IMP (9136933)
GO:0006350	transcription	Biological Process	IEA
GO:0006355	regulation of transcription, DNA-dependent	Biological Process	IDA (9738004)
GO:0006357	regulation of transcription from RNA polymerase II promoter	Biological Process	IDA (15082719)
GO:0007267	cell-cell signaling	Biological Process	IMP (16127717)
GO:0007507	heart development	Biological Process	IMP (11297508\|15464586)
GO:0001701	in utero embryonic development	Biological Process	IMP (9136932\|9136933\|15310850)
GO:0035050	embryonic heart tube development	Biological Process	IMP (9136932\|9136933)
GO:0048617	embryonic foregut morphogenesis	Biological Process	IMP (9136932\|9136933)