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Gene Information
Gene ID:14633
Symbol:Gli2
Full Name:GLI-Kruppel family member GLI2
Alias:AW546128
Organism:Mus musculus (Mouse)
Chromosome:1
Genetic Location:1 E2-E4|1 63.0 cM
Physical Location:120730637-120950195 on NC_000067.5, complement
Gene Type:protein-coding
Human Ortholog:GeneID: 2736    Symbol (Name): GLI2 (GLI-Kruppel family member GLI2)
Ortholog Status:The human GeneID 2736 is not in current human dataset.
Gene in Ethanol Study Datasets
QTL Information
QTLPhenotypeChrPeak (cM)LODP ValueRangeStatusQTL Link
Ap1qAlcohol Preference Drinking17645-95 (cM)4.5 SignificantPARC
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_001081125.1NP_001074594.1NC_000067.5 range: 120730637..120950195, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005634nucleusCellular ComponentIDA (16316410)
GO:0005737cytoplasmCellular ComponentIGI (16316410)
GO:0005634nucleusCellular ComponentRCA (12466851)
GO:0003682chromatin bindingMolecular FunctionIDA (16396903)
GO:0003713transcription coactivator activityMolecular FunctionRCA (12466851)
GO:0003700transcription factor activityMolecular FunctionRCA (12466851)
GO:0003700transcription factor activityMolecular FunctionIDA (16880529)
GO:0043565sequence-specific DNA bindingMolecular FunctionIDA (16611981)
GO:0003677DNA bindingMolecular FunctionRCA (12466851)
GO:0003677DNA bindingMolecular FunctionIDA (15614767|16880529)
GO:0042475odontogenesis of dentine-containing teethBiological ProcessIGI (9655803)
GO:0035295tube developmentBiological ProcessIGI (9731531)
GO:0030902hindbrain developmentBiological ProcessIMP (8575294|15496441)
GO:0030902hindbrain developmentBiological ProcessIGI (15496441)
GO:0030879mammary gland developmentBiological ProcessIMP (11783999)
GO:0030324lung developmentBiological ProcessIMP (9731531)
GO:0030324lung developmentBiological ProcessIGI (10725236)
GO:0021938smoothened signaling pathway in regulation of granule cell precursor cell proliferationBiological ProcessIGI (16571625)
GO:0021938smoothened signaling pathway in regulation of granule cell precursor cell proliferationBiological ProcessIMP (16571625)
GO:0021965spinal cord ventral commissure morphogenesisBiological ProcessIMP (10409510)
GO:0021983pituitary gland developmentBiological ProcessIGI (10725236)
GO:0030154cell differentiationBiological ProcessIMP (9636069|9655799)
GO:0042475odontogenesis of dentine-containing teethBiological ProcessIMP (9655803)
GO:0045666positive regulation of neuron differentiationBiological ProcessIGI (16950124)
GO:0060032notochord regressionBiological ProcessIGI (10725236)
GO:0048856anatomical structure developmentBiological ProcessIMP (11485934)
GO:0048856anatomical structure developmentBiological ProcessIGI (11485934)
GO:0048754branching morphogenesis of a tubeBiological ProcessIMP (9731531)
GO:0048666neuron developmentBiological ProcessIMP (16267219)
GO:0048646anatomical structure formationBiological ProcessIGI (9731531)
GO:0048589developmental growthBiological ProcessIMP (16571630)
GO:0048566embryonic gut developmentBiological ProcessIMP (10693670)
GO:0045944positive regulation of transcription from RNA polymerase II promoterBiological ProcessIGI (16880529)
GO:0045944positive regulation of transcription from RNA polymerase II promoterBiological ProcessIDA (16611981|16880529|16950124)
GO:0045941positive regulation of transcriptionBiological ProcessIDA (15614767)
GO:0021904dorsoventral neural tube patterningBiological ProcessIDA (9247260)
GO:0021776smoothened signaling pathway involved in spinal cord motor neuron cell fate specificationBiological ProcessIGI (15215207)
GO:0007418ventral midline developmentBiological ProcessIMP (10725236)
GO:0007418ventral midline developmentBiological ProcessIGI (10725236)
GO:0007411axon guidanceBiological ProcessIMP (10409510)
GO:0007389pattern specification processBiological ProcessIMP (8575294)
GO:0007389pattern specification processBiological ProcessIGI (14602680)
GO:0007165signal transductionBiological ProcessRCA (12466851)
GO:0006355regulation of transcription, DNA-dependentBiological ProcessRCA (12466851)
GO:0000122negative regulation of transcription from RNA polymerase II promoterBiological ProcessIGI (16611981)
GO:0002076osteoblast developmentBiological ProcessIMP (16880529)
GO:0002076osteoblast developmentBiological ProcessIDA (16880529)
GO:0001822kidney developmentBiological ProcessIGI (11172440)
GO:0007442hindgut morphogenesisBiological ProcessIGI (11485934)
GO:0007442hindgut morphogenesisBiological ProcessIMP (11485934)
GO:0007507heart developmentBiological ProcessIGI (11172440)
GO:0021775smoothened signaling pathway involved in ventral spinal cord interneuron specificationBiological ProcessIGI (15215207)
GO:0021696cerebellar cortex morphogenesisBiological ProcessIMP (16571625)
GO:0021696cerebellar cortex morphogenesisBiological ProcessIGI (16571625)
GO:0021517ventral spinal cord developmentBiological ProcessIMP (11748151)
GO:0021513spinal cord dorsal/ventral patterningBiological ProcessIMP (11748151|16364285)
GO:0021513spinal cord dorsal/ventral patterningBiological ProcessIGI (15215207|16364285)
GO:0021508floor plate formationBiological ProcessIMP (9636069|9655799)
GO:0009954proximal/distal pattern formationBiological ProcessIGI (16342201)
GO:0009953dorsal/ventral pattern formationBiological ProcessIGI (16342201)
GO:0008284positive regulation of cell proliferationBiological ProcessIMP (9731531|15496441)
GO:0008284positive regulation of cell proliferationBiological ProcessIGI (15496441|16054035)
GO:0001501skeletal developmentBiological ProcessIMP (9006072)
Other Database Cross Links
NCBI Entrez Gene:14633
MGI:
Ensembl:ENSMUSG00000048402
dbSNP:Gli2
AceView:Gli2