ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Got1

Full Name:

glutamate oxaloacetate transaminase 1, soluble

Alias:

AI789014|Got-1|cAspAT

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

19 C3|19 37.0 cM

Physical Location:

43574244-43598998 on NC_000085.5, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 2805 Symbol (Name): GOT1 (glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1))

Ortholog Status:

The human GeneID 2805 is not in current human dataset.

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Calw2/Alcdp2	Chronic Alcohol Withdrawal	19	47	36.5-ter (cM)	5.3	6.00E-07	Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_010324.2	NP_034454.2	NC_000085.5 range: 43574244..43598998, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005737	cytoplasm	Cellular Component	IEA
GO:0005829	cytosol	Cellular Component	IDA (4193185)
GO:0003824	catalytic activity	Molecular Function	IEA
GO:0008483	transaminase activity	Molecular Function	IEA
GO:0016769	transferase activity, transferring nitrogenous groups	Molecular Function	IEA
GO:0030170	pyridoxal phosphate binding	Molecular Function	IEA
GO:0004609	phosphatidylserine decarboxylase activity	Molecular Function	IDA (3242498)
GO:0004069	aspartate transaminase activity	Molecular Function	IDA (1914521\|7444718\|17545671)
GO:0016740	transferase activity	Molecular Function	IEA
GO:0019551	glutamate catabolic process to 2-oxoglutarate	Biological Process	IDA (4193185)
GO:0019550	glutamate catabolic process to aspartate	Biological Process	IDA (4193185)
GO:0009058	biosynthetic process	Biological Process	IEA
GO:0006532	aspartate biosynthetic process	Biological Process	IDA (4193185)
GO:0006520	amino acid metabolic process	Biological Process	IEA
GO:0006114	glycerol biosynthetic process	Biological Process	IDA (17545671)
GO:0006107	oxaloacetate metabolic process	Biological Process	IDA (4193185)
GO:0055089	fatty acid homeostasis	Biological Process	IDA (17545671)