ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Grk5

Full Name:

G protein-coupled receptor kinase 5

Alias:

Gprk5

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

19 D3|19 55.0 cM

Physical Location:

60966378-61168244 on NC_000085.5

Gene Type:

protein-coding

Human Ortholog:

GeneID: 2869 Symbol (Name): GRK5 (G protein-coupled receptor kinase 5)

Ortholog Status:

The human GeneID 2869 is not in current human dataset.

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Calw2/Alcdp2	Chronic Alcohol Withdrawal	19	47	36.5-ter (cM)	5.3	6.00E-07	Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_018869.3	NP_061357.3	NC_000085.5 range: 60966378..61168244

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0000166	nucleotide binding	Molecular Function	IEA
GO:0016301	kinase activity	Molecular Function	IEA
GO:0005524	ATP binding	Molecular Function	IEA
GO:0004872	receptor activity	Molecular Function	IEA
GO:0004871	signal transducer activity	Molecular Function	RCA (12466851)
GO:0004703	G-protein coupled receptor kinase activity	Molecular Function	RCA (12466851)
GO:0004674	protein serine/threonine kinase activity	Molecular Function	RCA (12466851)
GO:0004672	protein kinase activity	Molecular Function	RCA (12466851)
GO:0016740	transferase activity	Molecular Function	IEA
GO:0006468	protein amino acid phosphorylation	Biological Process	RCA (12466851)
GO:0007165	signal transduction	Biological Process	RCA (12466851)