ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Gsr

Full Name:

glutathione reductase

Alias:

AI325518|D8Ertd238e|Gr-1|Gr1

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

8 A4|8 18.0 cM

Physical Location:

34763709-34808633 on NC_000074.5

Gene Type:

protein-coding

Human Ortholog:

GeneID: 2936 Symbol (Name): GSR (glutathione reductase)

Ortholog Status:

The human GeneID 2936 is also in human dataset(s).

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Caws3/Alcw6	Chronic Alcohol Withdrawal	8		16-43 (cM)	3.5	0.0003	Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_010344.4	NP_034474.4	NC_000074.5 range: 34763709..34808633

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005615	extracellular space	Cellular Component	RCA (12466851)
GO:0005737	cytoplasm	Cellular Component	IEA
GO:0005739	mitochondrion	Cellular Component	IDA (14651853)
GO:0004362	glutathione-disulfide reductase activity	Molecular Function	IDA (204065\|1235912\|2139228\|7323947)
GO:0050660	FAD binding	Molecular Function	IEA
GO:0016491	oxidoreductase activity	Molecular Function	IEA
GO:0009055	electron carrier activity	Molecular Function	IEA
GO:0050661	NADP binding	Molecular Function	IEA
GO:0045454	cell redox homeostasis	Biological Process	IEA
GO:0006749	glutathione metabolic process	Biological Process	IC (1235912)