ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Gucy2e

Full Name:

guanylate cyclase 2e

Alias:

GC-E|GC1|ROS-GC1

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

11 B3|11 37.0 cM

Physical Location:

69036536-69050146 on NC_000077.5, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 3000 Symbol (Name): GUCY2D (guanylate cyclase 2D, membrane (retina-specific))

Ortholog Status:

The human GeneID 3000 is not in current human dataset.

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Lore4	Alcohol-induced Loss of Righting Reflex	11		36-42 (cM)	6.5		Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_008192.2	NP_032218.2	NC_000077.5 range: 69036536..69050146, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005615	extracellular space	Cellular Component	RCA (12466851)
GO:0005624	membrane fraction	Cellular Component	TAS (8838319)
GO:0016021	integral to membrane	Cellular Component	RCA (12466851)
GO:0016020	membrane	Cellular Component	IEA
GO:0004383	guanylate cyclase activity	Molecular Function	IEA
GO:0004672	protein kinase activity	Molecular Function	IEA
GO:0005524	ATP binding	Molecular Function	IEA
GO:0016849	phosphorus-oxygen lyase activity	Molecular Function	IEA
GO:0016829	lyase activity	Molecular Function	IEA
GO:0009190	cyclic nucleotide biosynthetic process	Biological Process	IEA
GO:0007601	visual perception	Biological Process	IEA
GO:0007242	intracellular signaling cascade	Biological Process	IEA
GO:0006468	protein amino acid phosphorylation	Biological Process	IEA
GO:0006182	cGMP biosynthetic process	Biological Process	IEA
GO:0050896	response to stimulus	Biological Process	IEA