ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Hand1

Full Name:

heart and neural crest derivatives expressed transcript 1

Alias:

Ehand1|Hxt|Th1|Thing1|eHAND

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

11 B1.3|11 32.0 cM

Physical Location:

57642214-57645648 on NC_000077.5, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 9421 Symbol (Name): HAND1 (heart and neural crest derivatives expressed 1)

Ortholog Status:

The human GeneID 9421 is not in current human dataset.

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Caws4/Alcw3	Chronic Alcohol Withdrawal	11		15-36 (cM)	6.7	2.00E-07	Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_008213.2	NP_032239.1	NC_000077.5 range: 57642214..57645648, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005634	nucleus	Cellular Component	IDA (15509787)
GO:0016564	transcription repressor activity	Molecular Function	IGI (16759287)
GO:0030528	transcription regulator activity	Molecular Function	IDA (16759287)
GO:0042803	protein homodimerization activity	Molecular Function	IPI (15509787)
GO:0046982	protein heterodimerization activity	Molecular Function	IPI (15509787)
GO:0005515	protein binding	Molecular Function	IPI (15509787\|16759287)
GO:0003677	DNA binding	Molecular Function	IDA (15509787)
GO:0008134	transcription factor binding	Molecular Function	IPI (7814632)
GO:0045449	regulation of transcription	Biological Process	IEA
GO:0030154	cell differentiation	Biological Process	IGI (16759287)
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	Biological Process	IDA (15509787\|16759287)
GO:0007507	heart development	Biological Process	IMP (9500550\|15576406)
GO:0007507	heart development	Biological Process	IGI (15576406)
GO:0007275	multicellular organismal development	Biological Process	IEA
GO:0006355	regulation of transcription, DNA-dependent	Biological Process	IEA
GO:0006350	transcription	Biological Process	IEA
GO:0001707	mesoderm formation	Biological Process	IMP (9500550)
GO:0001525	angiogenesis	Biological Process	IMP (15073150)
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	Biological Process	IGI (16759287)