ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

SGOL2

Full Name:

shugoshin-like 2 (S. pombe)

Alias:

FLJ25211|MGC129665|TRIPIN

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

2q33.1

Physical Location:

201099184-201156749 on NC_000002.10

Gene Type:

protein-coding

Orthologs:

This gene has Mouse: 68549 ortholog(s) in other dataset(s).

Gene in Ethanol Study Datasets

Linkage Dataset

Marker

LOD

P value

Location (bp)

D2S117

195326948

Region:		195326948-216757195
Phenotype:		Alcoholism phenotype along with age, gender, and P300 or constraint
Name:		15211641
Method:		Linkage
Publication:		Hill et al. Am J Med Genet B Neuropsychiatr Genet. (2004) A genome wide search for alcoholism susceptibility genes. PubMed
Summary:		A total of 360 markers for 22 autosomes were spaced at an average distance of 9.4cMand genotyping performed for 330 members of these multiplex families. Extensive clinical data, personality variation, and event-related potential characteristics were available for reducing heterogeneity and detecting robust linkage signals. Multipoint linkage analysis using different analytic strategies give strong support for loci on chromosomes 1, 2, 6, 7, 10, 12, 14, 16, and 17. Thirty five markers with LOD score >2.0 at baseline using the binary alcoholism phenotype along with age, gender, and P300 or constraint (Table III). Here we listed the genes between two near markers or genes near a separate marker (within 2Mb).

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_152524.3	NP_689737.3	NC_000002.10 range: 201099184..201156749

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0000775	chromosome, pericentric region	Cellular Component	IEA
GO:0005634	nucleus	Cellular Component	IEA
GO:0030892	mitotic cohesin complex	Cellular Component	IDA (18084284)
GO:0005515	protein binding	Molecular Function	IPI (16541025\|17353931)
GO:0007049	cell cycle	Biological Process	IEA
GO:0007059	chromosome segregation	Biological Process	IEA
GO:0051301	cell division	Biological Process	IEA