ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

15211

Symbol:

Hexa

Full Name:

hexosaminidase A

Alias:

Hex-1

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

9 B|9 29.0 cM

Physical Location:

59387473-59412911 on NC_000075.5

Gene Type:

protein-coding

Human Ortholog:

GeneID: 3073 Symbol (Name): HEXA (hexosaminidase A (alpha polypeptide))

Ortholog Status:

The human GeneID 3073 is also in human dataset(s).

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Ap5q	Alcohol Preference Drinking	9	25	10-35 (cM)	4.8		Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_010421.4	NP_034551.2	NC_000075.5 range: 59387473..59412911

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0016020	membrane	Cellular Component	IDA (11854359)
GO:0005764	lysosome	Cellular Component	IDA (9645704\|11854359)
GO:0016787	hydrolase activity	Molecular Function	IEA
GO:0016798	hydrolase activity, acting on glycosyl bonds	Molecular Function	IEA
GO:0043169	cation binding	Molecular Function	IEA
GO:0046982	protein heterodimerization activity	Molecular Function	ISO
GO:0004563	beta-N-acetylhexosaminidase activity	Molecular Function	IMP (7937929\|8747922\|8789434\|10196372)
GO:0004563	beta-N-acetylhexosaminidase activity	Molecular Function	IGI (8896570)
GO:0003824	catalytic activity	Molecular Function	IEA
GO:0004563	beta-N-acetylhexosaminidase activity	Molecular Function	IDA (1914521\|8747922\|9417048\|11854359)
GO:0050884	neuromuscular process controlling posture	Biological Process	IMP (14972652)
GO:0019915	sequestering of lipid	Biological Process	IMP (9223328\|10021458\|14972652)
GO:0019953	sexual reproduction	Biological Process	IMP (9645704)
GO:0030203	glycosaminoglycan metabolic process	Biological Process	IGI (8896570)
GO:0042552	myelination	Biological Process	IGI (9184660)
GO:0001501	skeletal development	Biological Process	IGI (8896570\|9184660)
GO:0008152	metabolic process	Biological Process	IEA
GO:0007628	adult walking behavior	Biological Process	IMP (14972652)
GO:0007626	locomotory behavior	Biological Process	IGI (8896570)
GO:0007605	sensory perception of sound	Biological Process	IGI (8896570)
GO:0007040	lysosome organization and biogenesis	Biological Process	IMP (7937929\|8747922\|9103204\|9302266\|9645704\|10591619\|14972652)
GO:0007040	lysosome organization and biogenesis	Biological Process	IGI (8896570\|9184660)
GO:0006689	ganglioside catabolic process	Biological Process	IMP (7937929\|8789434\|9223328\|9645704)
GO:0005975	carbohydrate metabolic process	Biological Process	IEA
GO:0050885	neuromuscular process controlling balance	Biological Process	IGI (8896570)